Salinity as one of the most destructive abiotic stresses retards plant growth and performance, especially in arid and semi-arid areas. Sodium nitroprusside is a nitric oxide donor playing an important role in the growth and productivity of plants under normal conditions or under stress. Glycerol is one of the chemical pre-treatment used to enhance the tolerance of plants against environmental stress, especially salt stress. In order to investigate the possible effects of foliar application of glycerol and sodium nitroprusside on some morphological and physicochemical traits of promising pistachio rootstocks under salt stress, a factorial experiment was conducted as a completely randomized design in three replications in a greenhouse in shahrood in 2022. The rootstocks included Atlantica (P.atlantica), Integrima (P.integrima) and two promising genotypes of Arota (P.arota). The experiment included two factors. Salinity in three levels (0,100, 200 mM of sodium chloride) and stress moderators at five levels (30 and 60 mM of glycerol and 100 and 200 µM of sodium nitroprusside and control). The results indicated that the morphological traits decrease with the increase of salinity stress levels, while application of sodium nitroprusside could effectively compensate the deteriorative effects of salt stress. Glycerol did not reveal the same efficiency. It is concluded that effect of sodium nitroprusside was more pronounced in improving salt stress tolerance than glycerol